The top 20 upregulated genes such as DDIT4, THBD, PLIN2, JUN, MAFB, SIGLEC1 ABCA1, CXCR4, and MX1 and other and the top 20 downregulated genes for monocytes from breast cancer patients, log2FC ≥ 0.58, FDR ≤ 0.05, were found (Figures 3C, D). Here, SIGLEC1 is linked to breast cancer.