PTK6 and hepatocellular carcinoma: Moreover, Zhang et al. (2016) demonstrated that miR-187 inhibited the epithelial-mesenchymal transition (EMT) process via repressing the TGF-β/Smad pathway through targeting NT5E and PTK6 in colorectal carcinoma; Dou et al. (2016) also demonstrated that miR-187-3p could suppressed the metastasis and EMT of hepatocellular carcinoma.