Furthermore, iron load in colorectal cancer cells can promote the Wnt signaling and cell proliferation [40], but iron chelators, including deferoxamine, deferoxamine, and ciclopirox, can inactivate the Wnt signaling, and AML patients taking cyclohexanolamine show a significant decrease in the expression of the Wnt target gene AXIN2. This evidence concerns the gene AXIN2 and colorectal cancer.