We first analyzed expression levels in ccRCC of these seven genes, and in mRNA level, results from ONCOMINE showed except GMIP, IFI16, and TCIRG1 were overexpressed in ccRCC patients, while analysis based on TCGA indicated expression levels of CAPS and CLDN7 were significantly low in ccRCC patients, and BIRC5, CLVS1, GMIP, IFI16, and TCIRG1 were highly expressed in ccRCC patients. The gene discussed is CLVS1; the disease is nonpapillary renal cell carcinoma.