Comparing the mRNA expression levels of BIRC5, CAPS, CLDN7, CLVS1, GMIP, IFI16, and TCIRG1 in ccRCC patients and normal people, we found that BIRC5, CLVS1, GMIP, IFI16, and TCIRG1 were significantly overexpressed in ccRCC patients from TCGA-KIRC dataset and CAPS and CLDN7 had lower expression level in ccRCC patients than in normal people. Here, IFI16 is linked to nonpapillary renal cell carcinoma.