Results from GSEA analyzing functional enrichment of high and low risk group indicated that JAK-STAT signaling pathway, NOD-like receptor signaling pathway, and RIG-I-like receptor signaling pathway might be the cause of poorer prognosis of ccRCC patients (Smith et al., 2018; Mey et al., 2019; Zhou et al., 2020). Here, SOAT1 is linked to nonpapillary renal cell carcinoma.