LRPPRC and neoplasm: Leucine-rich pentatricopeptide repeat-containing (LRPPRC), also known as LRP130, is a member of the pentatricopeptide repeat protein family and exerts multiple functions involving homeostasis, microtubule alterations, RNA stability, DNA/RNA binding, transcriptional activity in mitochondria, metabolic processes, RNA nuclear export, tumorigenesis, and tumor progression (Ghiso and Lennon, 1994; Tsuchiya et al., 2002; Mili and Piñol-Roma, 2003; Mootha et al., 2003; Michaud et al., 2011).