Compared with the GFAP and STAT3 levels in the CCH group, the expression in the SCH58261 group were significantly higher and those in the CGS21680 group were significantly lower, indicating that ADORA2A prevented the expression of STAT3 mediated by activation of the astrocytes (Figures 3B–D). The gene discussed is GFAP; the disease is columnar cell hyperplasia of the breast.