MALAT1 and fibrosis: Detection by qRT-PCR showed that relative expression of plasma EVs-Lnc-MALAT1 was 0.089, 0.208, and 2.068 in the control, the low fibrosis and the high fibrosis patients, respectively, showing that relative expression of plasma EVs-Lnc-MALAT1 was correlated with liver fibrogenesis (Figure 1E).