It is worth mentioning that bio-products based on Citrus help in glycemic control (Mollace et al., 2011; Ding et al., 2012; Kim et al., 2013; Lu et al., 2013; Raasmaja et al., 2013; Muhtadi et al., 2015; Dinesh and Hegde, 2016; Ashraf et al., 2017; Fayek et al., 2017), possibly by reducing resistin (Kim et al., 2013), an adipocytokine whose increase has been associated with insulin resistance, atherosclerosis, oxidative stress, and inflammation. The gene discussed is RETN; the disease is atherosclerosis.