NR4A2 and adenocarcinoma: Therefore, proteins such as the transcription factor NR4A2 whose suppression has been linked to the gastrointestinal inflammation and adenocarcinoma (Han and Cao, 2012; Mohan et al., 2012; Yeh et al., 2016), and the A20 protein, an NFκB inhibitor (Kuzuhara et al., 2007a) may indicate promising candidates for further analysis on Tipα activity and pathogenesis.