Resveratrol shows its anti-rheumatoid arthritis properties with reduced RA patients’ swelling, tenderness, and disease activity by lowering the biochemical indicators of inflammation like MMP-3, IL-6, ESR, C-reactive protein, and undercarboxylated osteocalcin (Khojah et al., 2018; Meng et al., 2021). This evidence concerns the gene CRP and rheumatoid arthritis.