Table 3 and Figure 2 show a comparison of biomarker concentrations between groups. Aβ42 was decreased in both the AD and CAA group when compared to the control group but there was no significant difference between CAA and AD. Aβ40 did not differ significantly between CAA, AD, and controls. T-tau and p-tau181 were highest in the AD group followed by the CAA group and controls and all group differences were significant (Figure 2). This evidence concerns the gene MAPT and Alzheimer disease.