After accounting for the effects of age, sex, differentiation, tumor status, stage and lymph node metastasis, multivariate Cox regression analysis indicated that the level of FUT8 expression was an independent predictor of poor OS (HR = 2.87; 95% CI = 1.42–5.77; p = .003; Table 4). The gene discussed is FUT8; the disease is metastatic malignant neoplasm in the lymph nodes.