SERPINH1 and colitis: The bacteria can express the collagen-binding protein (CBP), which is more common in patients with bacteremia after tooth extraction and infective endocarditis.41 Animal experiments have found that jugular vein injection of Streptococcus mutans TW295 can aggravate the degree of inflammation in a mouse model of colitis.42 According to clinical research, the detection rate of this strain in patients with colitis is also higher than that of healthy people.