CD80 and Fabry disease: Other potential biomarkers in FD include plasma 3-nitrotyrosine, podocyturia and urinary excretion of CD80 [145, 146], while sphingosine-1-phosphate (S1P) was recently identified as a biologically active growth-promoting factor involved in cardiovascular remodeling in both males and females with FD plasma levels of which show a strong correlation with LVM index, and increased common carotid artery intima-media thickness [147].