Therefore, we examined the differentially expressed circRNAs associated with RBFOX1 and found that downregulation of hsa_circ_0111312 in GBM was strongly correlated with decreased RBFOX1 expression in GBM (Additional file 4: Fig. S10C), independent of expression of its host gene RASAL2 (Additional file 4: Fig. S10D). This evidence concerns the gene RBFOX1 and glioblastoma.