CXCL8 and hepatocellular carcinoma: Moreover, TQ could stunt the growth of HCC cell lines through the generation of ROS, heme oxygenase-1 (HO-1), and aNAD(P)H quinone dehydrogenase-1 (NQO1) as well as inactivation of Bcl-2, IL-8, and their receptors [55].