CD4 and hepatocellular carcinoma: In both the enriched and decreased subgroups of B cells (Fig. 5B, I), CD4+ T cells (Fig. 5C, I) macrophages (Fig. 5D, I), natural killer T cells (Fig. 5E, I), regulatory T cells (Fig. 5F, I) and type-1 T-helper cells (Fig. 5G, I), high ROBO1 expression was significantly correlated with poor OS in HCC patients.