As shown in Table 2, ROBO1 was significantly positively correlated with T-helper cell biomarkers (CXCR3, CCR4, CCR6 and CCR10), Tcm biomarkers (CD62L, CCR5, CD58 and TCF7), Th2 cell biomarkers (PTGDR2, IL5 and IL10) and macrophage biomarkers (PPARG, IRF5 and CD68) in HCC. The gene discussed is CCR5; the disease is hepatocellular carcinoma.