It is noteworthy that the lncRNA-miRNA-mRNA network was formed between hsa-miR-144-3p, CCNE2, C9orf72, LEF1-AS1, MAP3K20-AS1, AC239798.2, AC243772.2, and FLJ46284, which may play an important role in regulating CF and HF through mutual regulation. The gene discussed is CCNE2; the disease is cystic fibrosis.