The identification of hsa-miR-144-3p, CCNE2, C9orf72, MAP3K20-AS1, LEF1-AS1, AC243772.2, FLJ46284, and AC239798.2 in the lcRNA-miRNA-mRNA network implies that they may be involved in the progression from CF to HF. The gene discussed is LEF1; the disease is hydrops fetalis.