We were curious whether the stable CENP-A signature we detected by chromatin immunoprecipitation sequencing (ChIP-seq) and IF/FISH at the 8q24 locus could also be linked to well-documented hyperactive transcription of 8q24-specific noncoding genes in several types of cancer cells, including colon tumors (42). The gene discussed is CENPA; the disease is colonic neoplasm.