CRYAB has been reported to be a marker of poor prognosis in breast cancer (Ivanov et al. 2008; Moyano et al. 2006; Voduc et al. 2015) and has oncogenic potential (Moyano et al. 2006), although this is open to discussion (Zoppino et al. 2018). The gene discussed is CRYAB; the disease is breast carcinoma.