CD81 and acute respiratory distress syndrome: In patients with sepsis-related ARDS, those who died within 30 days of intensive care unit (ICU) admission had a greater number of CD14+/CD81+ BAL EV than survivors (Fig. 3A, medians 3.43 × 108/mL vs. 9.54 × 107/mL, P = 0.027), however there is overlap between groups.