Because androgen‐bound AR alters mRNA expression of many molecular exercise transducers, for example, myogenesis,51 and is associated with triggering anabolic kinase signalling, that is, Akt, the fact that its expression is blunted at both the gene and protein levels with hypogonadism would suggest translational and transcriptional links between endogenous T and changes in MPS, FFM, and strength in this present study and others.12, 49. This evidence concerns the gene AKT1 and hypogonadism.