While mRNA expression of select myogenesis‐related genes, that is, myogenin (Z: P > 0.99 vs. P: P = 0.002, ES = 0.72, treatment‐by‐time interaction: P = 0.05), Myf‐5 (Z: P = 0.34 vs. P: P = 0.0001, ES = 0.81, treatment‐by‐time interaction: P = 0.07), and Myf‐6 (Z: P = 0.11 vs. P: P = 0.01, ES = 0.79, treatment‐by‐time interaction: P = 0.01), were not changed with hypogonadism compared with P, C‐met (Z: P = 0.03 vs P: P < 0.0001, ES = Z:0.77, P:0.82) and C‐Myc (Z: P = 0.007 vs. P: P = 0.01, ES = Z:0.74, P:0.74) increased in both groups, with no significant changes in MYOD and PAX‐7 (P > 0.05). This evidence concerns the gene MYF6 and hypogonadism.