In contrast, an irinotecan‐containing chemotherapy regimen (carboplatin, dexamethasone, etoposide, and irinotecan [CDE‐11]) for adult diffuse large B‐cell lymphoma has been shown to improve prognosis in patients with the UGT1A1*6 polymorphism.23 The gene discussed is UGT1A1; the disease is diffuse large B-cell lymphoma.