In addition, the cellular and molecular responses to seasonal influenza vaccination and the associated kinetics have been well characterized in healthy adults, including early innate/inflammatory and interferon (IFN) responses on day 1 (D1) after vaccination and a strong but transient plasmablast peak around day 7 (D7) culminating in the generation of influenza-specific antibodies26–29. The gene discussed is IFNA1; the disease is influenza.