Moreover, the transcription level of GPC2 in the COAD tissues of the patients at advanced TNM stage was higher than that of the patients at early TNM stage, the GPC2 transcription level of patients with lymph node metastasis was higher than that of patients without lymph node metastasis, and the GPC2 transcription level in COAD tissue of patients with advanced T stage was higher than that of patients with early T stage (Figure 2j–l). The gene discussed is GPC2; the disease is metastatic malignant neoplasm in the lymph nodes.