To explore whether circ_AKT3 could regulate PTPN14 in DDP-resistant GC cells, MKN-7/DDP and HGC-27/DDP cells were transfected with si-NC, si-circ_AKT3, si-circ_AKT3 + anti-miR-NC or anti-miR-206. Here, AKT3 is linked to gastric cancer.