These included modifiers of SARS-CoV-2 cytopathic effect in recently reported CRISPR screens [29–36], genes in proximity to human GWAS loci associated with COVID-19 susceptibility [37] (S2 Table), genes we previously identified by RNA-seq whose correlation was associated with ACE2 expression in sorted HuH7 cells [28], candidates identified in our own pilot genome-wide CRISPR screens for ACE2 abundance (S1 Fig and S3 and S4 Tables), and a set of hypothesis-driven manually selected genes. Here, ACE2 is linked to COVID-19.