CD47 and cancer: By contrast, CD47 was among a set of genes showing increased expression in SIRPγhi A549 and H1975 cells compared with SIRPγlo/– cells selected by flow cytometry (Figure 5, D–F, and Supplemental Figure 5B) and SIRPγ-overexpressing cancer cells (Figure 5, G and H, and Supplemental Figure 5, C and E).