Th2 cell was proposed to promote tumor progression through the secretion of cytokines interleukin (IL)‐4, IL‐6, IL‐10, and IL‐13 to activate tumor‐associated M2 macrophages [42], and which was found to be a risk factor of male patients in SARC, LUAD, KIRP, PAAD, KIRC, and LIHC (HR > 1, Wald P < 0.05). The gene discussed is IL4; the disease is neoplasm.