Earlier studies, set out to examine AT1R in rat, mice, or human liver, were designed to determine AGTR1 expression and AT1R protein synthesis depending on the stage of liver disorder such as fibrosis, cirrhosis, cholestasis, or NAFDL (Schulte et al. 2009; Paizis et al. 2002; Afroze et al. 2015; Leung et al. 2003). The gene discussed is AGTR1; the disease is cholestasis.