KLK3 and metastatic neoplasm: However, compared with the global ITT population, Asian patients in the olaparib arm had a lower median weight (68.2 vs. 78.0 kg), higher rate of metastatic disease at initial diagnosis (62.1% vs. 25.7%), higher median prostate-specific antigen (PSA) at baseline (167.0 vs. 68.2 μg/L) and higher rate of visceral metastasis (36.3% vs. 26.6%).