However, we matched the demographic information on age and sex to achieve a balance between the study and control groups; we matched the type and number of oral antidiabetic drugs, insulin use, and DCSI scores to balance the severity of T2D; we have matched the comorbidity of CKD to decrease the influence of renal function on outcomes, and further increase the comparability between the study and control groups. Here, INS is linked to type 2 diabetes mellitus.