With the confirmation of the depletions of given TIL-lineages, we then monitored the growth kinetics of all four syngeneic tumors with and without depletion (Fig. 1B), with % TGI summarized in Table 1 Experiment 1 and Fig. 1C showing relative changes compared to untreated.MC38 tumor: Depletion of CD8+ TIL seemed to result in a slight increase in tumor growth (TGI -12%, Table 1 Experiment 1) and NK cell depletion had a slight decrease in tumor growth (TGI 13%). The gene discussed is CD8A; the disease is neoplasm.