As anticipated, lung tumors in KT;Lkb1XTR/XTR mice were adenomas and adenocarcinomas that express NKX2-1, a marker of adenocarcinoma differentiation, with only rare clusters of poorly differentiated cancer cells at late time points (Supplementary Fig. 2l, m)36,43,44. The gene discussed is NKX2-1; the disease is adenoma.