CEBPA and neoplasm: To validate the tumor-suppressive capacity of C/EBP factors, we initiated tumors in KT and KT;H11LSL-Cas9 mice with either Lenti-sgNeo1-sgNT-sgNeo2/Cre (Lenti-sgInert/Cre) or Lenti-sgCebpa-sgCebpb-sgCepbd/Cre (Lenti-sgCebpa/b/d/Cre) (Fig. 5c).