On the other hand, it has been reported to reduce fibrogenic signaling by the inhibition of the TGF-β signaling pathway17⁠ and to combat acute inflammatory insult, reducing severe sepsis-related mortality through the inhibition of NFkB signaling and the suppression of lipopolysaccharide-induced MAPK signaling18,19, which are key contributors to complications related to COVID-19. Here, NFKB1 is linked to COVID-19.