We searched for the underlying causes of increased EIF4EBP1 mRNA expression in malignant gliomas and observed that the EIF4EBP1 gene is not amplified in glioblastomas although amplification of 8p11.23, which encompasses EIF4EBP1, has been reported in other cancer entities, such as lung squamous cell carcinoma, bladder cancer, and breast cancer, and correlated with higher EIF4EBP1 expression [49]. The gene discussed is EIF4EBP1; the disease is cancer.