Finally, we analyzed existing ChIP-sequencing (seq) data from the Encode consortium [41, 42], which demonstrated direct binding of FOXM1, ETS1, E2F1, and E2F6 to the EIF4EBP1 promoter region, exon 1 and intron 1 (−1500 to +1000) in various normal and cancer cells, however not including glioblastoma cells (Fig. 2H). The gene discussed is E2F1; the disease is cancer.