While approximately 8.5% of TCGA malignant glioma cases analyzed here exhibited a low-level gain of EIF4EBP1 [33, 34], there was no association with higher EIF4EBP1 mRNA expression as compared to tumors without EIF4EBP1 copy number gain (Fig. 1B and Table S1). Here, EIF4EBP1 is linked to malignant glioma.