PECAM1 and triple-A syndrome: Naringenin administered via gavage induced a significant increase in lysosome number within F4/80+ macrophages but not in CD31+ ECs in the abdominal aorta of the CaPO4-induced mouse model of AAA, as evidenced by LysoTracker plus F4/80 or CD31 staining (Fig. 3g, Supplementary Fig. S2f).