Additionally, available tumor DNAs were studied using the mentioned gene panel and the somatic variants found were in agreement with each cancer type, including a splicing variant in PTEN in the lung adenocarcinoma sample, and BRAF p.(V600E) and PIK3CA p.(G1049R) in thyroid cancer samples (Additional file 1: Table S9). This evidence concerns the gene BRAF and thyroid gland carcinoma.