Alterations in RAD21 were enriched in high telomeric content samples from three breast cancer histologies, breast invasive lobular carcinoma (OR = 5.9), breast invasive ductal carcinoma (OR = 1.5), and breast carcinoma (nos) (OR = 1.5, Fig. 2A), as well as prostate acinar adenocarcinoma (OR = 2.7), and lung adenocarcinoma (OR = 1.7). The gene discussed is RAD21; the disease is breast carcinoma.