First, from the C-T-P (compounds-target-pathway) network diagram, targets were sorted into EGFR, MET, MMP1, MMP3, NQO1, and MPO based on the number of regulatory pathways and corresponding components, and pathways were ranked into pathways in cancer, transcriptional misregulation in cancer, hepatocellular carcinoma, bladder cancer, and EGFR tyrosine kinase inhibitor resistance. This evidence concerns the gene MMP3 and hepatocellular carcinoma.