Based on the above-mentioned analysis, three targets, included Hsp90AA1, PTGS2, and MMP2 were excluded, and previous studies have shown that Hsp90AA1 and the isotype Asp90AB1 may be required for the treatment of two subtypes of breast cancer (MCF-7 and BT-474) [31]. This evidence concerns the gene PTGS2 and breast carcinoma.