The results show that some proteins functionally enriched to cell-cell adherens junctions [56], the cell cycle, and G2/M checkpoints [57], whereas signaling pathway enrichment included the Rho GTPase signaling pathway [58], VEGFA/VEGFR signaling pathway [59], noncanonical NF-κB signaling [60], WNT/β-catenin signaling pathway [61], and PI3K/Akt signaling pathway [53], all of which are closely related to tumor metastasis and proliferation. This evidence concerns the gene AKT1 and neoplasm.