Further to explore the relationship of the miR-106a-5p/SOX4 axis with HOTAIR in NPC DDP-resistant cells, we found that si-SOX4 inhibited the increased IC50 values induced by miR-106a-5p inhibitors (Figure 6(a,b)), as well as the increased apoptosis (Figure 6(c)). Here, SOX4 is linked to nasopharyngeal carcinoma.