In contrast, most features associated with 4T1 tumour growth were significantly different from normal levels in Nil animals, with G-CSF level and neutrophil count being >10-fold higher, PD-L1+ myeloid cell count being ~2-fold higher, and both CXCL13 and IL-6 levels being ~<2-fold higher than normal (Fig 5). This evidence concerns the gene CSF3 and neoplasm.