Data revealed that DLBCL patients with stages I and II did not have significant changes in the percentages of cells, whereas DLBCL patients with stages III and IV presented higher PD-L1+CD20+ %, in which stage IV revealed significantly increased percentages of PD-L1+CD20+ cells than stages I and II (p = 0.001) (Figure 3G). The gene discussed is CD274; the disease is diffuse large B-cell lymphoma.