MBOAT7 and metabolic dysfunction-associated steatotic liver disease: In relation to liver disease, several studies have seen that LPLAT11 (MBOAT7) mutations are associated with development and severity of non-alcoholic fatty liver disease (NAFLD) [70–72], while mice selectively lacking liver LPLAT12 (MBOAT5) show many hepatic alterations including development of steatosis on a chow diet [50] (http://www.informatics.jax.org/diseasePortal/genoCluster/view/57 246).