As shown in Figure 5(A–B), we found that the expression of proapoptotic proteins, such as c-PARP1, BAX and c-caspase 3, and ER associated caspase 12 were significantly increased, while the level of antiapoptotic protein, Bcl2, was decreased in the AKI group compared with the sham group. The gene discussed is BCL2; the disease is acute kidney injury.