AKT1 and cancer: Some researchers indicated that 10 μM of Tel or 2 μM of this drug in combination with 2 μM of Gefitinib, a selective inhibitor of epidermal growth factor receptor tyrosine kinase, via upregulation of phosphatase and tensin homologue (PTEN) transcription can inhibit the PI3K/AKT pathway in cancer cells.43, 44