With the exception of the preoperative MOCA score, no significant differences in the baseline characteristic data were observed between the three groups, such as sex, age, BMI, SBP, DBP, hemoglobin level, ESR, CRP level, hemameba level, neutrophil counts, ASA classification, and comorbidities (including arrhythmia, hypertension, diabetes, CHD, history of stroke, and digestive system disease) (Table 1). This evidence concerns the gene CRP and cardiac arrhythmia.