Furthermore, the significant KEGG pathway (Figures 7C,D) mainly focus on “MAPK signaling pathway” (NES = 1.863, FDR = 0.005), PI3K-Akt signaling pathway (NES = 1.790, FDR = 0.012), and amyotrophic lateral sclerosis (NES = −2.002, FDR = 0.009). This evidence concerns the gene AKT1 and amyotrophic lateral sclerosis.