The most recent National Comprehensive Cancer Network (NCCN) guideline recommendations (Version 5.2021) for the management of NSCLC now include testing for EGFR, BRAF, ALK, ROS1, RET, KRAS, MET exon 14 skipping, and NTRK in nonsquamous lung cancer, as part of broader molecular profiling (8). The gene discussed is BRAF; the disease is non-small cell lung carcinoma.